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Advantage Multi for Dogs is a topical treatment that protects against fleas, worms, and heartworm disease in dogs and puppies at least 7 weeks of age and weighing at least 3 lbs.
When applied to the dog’s skin, this easy-to-administer spot-on helps prevent heartworm disease, treats circulating microfilariae, and kills adult fleas. It rapidly eliminates fleas and treats existing infestations, helping to break the flea life cycle and reduce reinfestations.
It also treats and controls sarcoptic mange and intestinal parasite infections caused by hookworms, roundworms, and whipworms. With its broad-spectrum protection and convenient monthly application, Advantage Multi offers a reliable way to safeguard your dog from both external and internal parasites.
Advantage Multi for Dogs contains two active ingredients that work together to provide comprehensive parasite protection:
After application, the solution spreads across the skin and coat, allowing imidacloprid to control external parasites while moxidectin provides internal protection.
| Dog Size | Dog Weight | Dose Per Month | Dose Volume (mL) | Imidacloprid (mg) | Moxidectin (mg) |
| Small Dogs | 3-9 lbs | One | 0.4 | 40 | 10 |
| Medium Dogs | 9.1-20 lbs | One | 1.0 | 100 | 25 |
| Large Dogs | 20.1–55 lbs | One | 2.5 | 250 | 62.5 |
| Extra Large Dogs | 55.1–88 lbs | One | 4.0 | 400 | 100 |
| Over 88 lbs | - | Use appropriate combination | - | - | - |
| Target Species | Dogs |
| Treatment Type | Internal and External Parasite Protection |
| Product Form | Liquid |
| Effective Against | Fleas, Heartworms, Roundworms, Hookworms, Whipworms, Sarcoptic Mange |
| Dosing Frequency | Monthly |
| Mode of Administration | Topical |
| Active Ingredients | Imidacloprid, Moxidectin |
Advantage Multi (Advocate) is a broad-spectrum parasite treatment for dogs that prevents heartworm infections and treats heartworm larvae, kills fleas, and treats intestinal worms, including roundworms, hookworms, and whipworms. It is also effective in the treatment of sarcoptic mange.
When Advantage Multi (Advocate) is applied to the skin, it spreads over your dog’s body to kill fleas through contact. Fleas don’t have to bite your dog to die with Advantage Multi.
Advantage Multi lasts for one full month. It should be given every month year-round for complete prevention against heartworm and fleas.
It is not recommended to treat heartworm-positive dogs with Advantage Multi without your vet’s consultation. It is advisable to check with the vet first for proper diagnosis and then continue the treatment once the vet approves.
Yes, Advantage Multi treats and controls hookworm infections in dogs.
Advantage Multi covers hookworms (Ancylostoma caninum, Uncinaria stenocephala), roundworms (Toxocara canis, Toxascaris leonina), and whipworms (Trichuris vulpis).
Advantage protects dogs from fleas and lice, whereas Advantage Multi contains an additional ingredient (moxidectin) that protects against heartworm disease and intestinal worms.
Advantage Multi is applied on the back of the dog at the skin between the shoulder blades.
It is recommended to bathe your dog before applying the product. Shampooing 90 minutes after application does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
It is not recommended to use Advantage Multi for Dogs on cats. Use only products specifically labeled for cats, as dog products can be harmful or toxic to cats.
You can buy Advantage Multi for Dogs online from trusted stores like CanadaVetExpress or from your veterinarian.
Note: All the product-related information is based solely on the official label and manufacturer-provided details. It does not replace professional veterinary advice. Please consult your veterinarian before starting any treatment.
Still Have Questions? – Please email us your queries at support@canadavetexpress.com and we will be happy to help you.
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The largest size we carry for Advocate is Advantage Multi (Advocate) Extra Large Dogs 55.1-88 lbs (Blue).
We will update it on our website if we start carrying Advantage Multi (Advocate) for more than 88 lbs of dogs. However, if your dog weighs more than 88 lbs, you can administer an appropriate combination of Advocate doses on your dogs after consulting with a vet.
Currently, the largest pack size for Advantage Multi (Advocate) for Dogs we carry is for Extra Large Dogs weighing between 55.1-88 lbs (Blue Pack)
Advantage Multi (Advocate) Large Dogs 20.1-55 lbs (Red)
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