- Where is my order

- Cancel Order

- Track my order

- Issue with my order

- Call me now
- Schedule the call
- Our shipping policy

- Our privacy policy

- Our terms and conditions

- Our guarantee

- Our order delivery time


Heartgard Plus Chewables for Dogs is a veterinarian-recommended monthly chew that helps prevent heartworm disease and treats and controls common intestinal worm infections in dogs and puppies 6 weeks of age and older.
Given once a month as a treat, the delicious, real-beef flavored chew helps prevent heartworm disease caused by Dirofilaria immitis, a serious infection that can damage a dog’s lungs and heart if left untreated.
In addition to heartworm prevention, Heartgard Plus treats and controls two species of roundworms and three species of hookworms, helping support your dog’s overall health year-round.
Heartgard Plus is formulated with two key ingredients:
When administered monthly, these ingredients work together to interrupt the parasite life cycle and help protect your dog from intestinal and heartworm infections.
Nuheart is a generic alternative to Heartgard that contains ivermectin for the prevention of heartworm disease in dogs. When administered monthly as directed, Nuheart helps eliminate developing heartworm larvae (Dirofilaria immitis) and prevents them from maturing into adult heartworms. Suitable for puppies and dogs 6 weeks of age and older, Nuheart provides reliable protection against heartworm infection.
Note: Unlike Heartgard Plus, Nuheart contains ivermectin only for heartworm disease prevention. It does not treat intestinal worms.
| Pack Color | Dog Weight | Dog Size | Dosage | Dosage strength |
| Heartgard Plus Blue | Up to 25 lbs | Small Dogs | One chew per month | 68 mcg of Ivermectin and 57 mg of Pyrantel |
| Heartgard Plus Green | 26 to 50 lbs | Medium Dogs | One chew per month | 136 mcg of Ivermectin and 114 mg of Pyrantel |
| Heartgard Plus Brown | 51 to 100 lbs | Large Dogs | One chew per month | 272 mcg of Ivermectin and 227 mg of Pyrantel |
| Dog Weight (lbs) | Dog Size | Dosage per Month |
| Up to 25 lbs | Small | Administer one tablet |
| 26 to 50 lbs | Medium | Administer one tablet |
| 51 to 100 lbs | Large | Administer one tablet |
* Use the appropriate combination of these chewables for dogs over 100 lbs.
| Target species | Dogs and puppies 6 weeks of age and older |
| Available pack sizes | Small, Medium, Large |
| Mode of administration | Oral |
| Effective For | Internal parasites (heartworms, roundworms, and hookworms) |
| Active Ingredient | Ivermectin and Pyrantel |
| Brand Name | Heartgard Plus for Dogs |
When used as directed, Heartgard Plus is safe and effective for dogs and puppies 6 weeks of age and older. However, some herding breeds (such as Collies) may have increased sensitivity to high doses of ivermectin due to MDR1 gene mutations. Heartgard Plus contains a low, preventive dose considered safe when used as directed. Additionally, all dogs should be tested for heartworm infection before starting a preventive program.
Heartgard Plus Chew contains ivermectin and pyrantel. Both these active ingredients work to protect your dog from immature heartworm larvae and intestinal worms like roundworms and hookworms.
Heartgard Plus is recommended for dogs and puppies at least 6 weeks of age. Always consult a vet before starting the treatment.
No, Heartgard Plus does not kill whipworms in dogs.
No, Heartgard Plus Chewable Tablet does not kill fleas and ticks. It is specifically designed to prevent heartworm infection and protect dogs against the dangers of heartworm disease.
Heartgard Plus Chew can be used alongside a flea and tick treatment like NexGard or Frontline Plus with a vet’s consultation.
When used as directed, Heartgard Plus Chewables have a wide safety margin in all breeds of dogs, including breeding, lactating, or pregnant dogs and puppies 6 weeks or older.
Please consult your vet if you have missed giving a dose. If a dose is missed or delayed, give Heartgard Plus as soon as possible and then resume the regular monthly dosing schedule to reduce the risk of adult heartworm development.
Heartgard Plus should be given regularly every month.
You can buy Heartgard Plus from your veterinarian or a trusted online store like CanadaVetExpress.
Note: All the product-related information is based solely on the official label and manufacturer-provided details. It does not replace professional veterinary advice. Please consult your veterinarian before starting any treatment.
Still Have Questions? – Please email us your queries at support@canadavetexpress.com and we will be happy to help you.
503 reviews
Share your thoughts with other customers
Write Review
Heartgard Plus Chewables Small Dogs up to 25lbs (Blue) we have has a short shelf life. To help you plan your purchase, we have mentioned the expiration date of the same.
Heartgard Plus for Large dogs is suitable for dogs weighing between 51 and 100 lbs.
Heartgard Plus comes in 6 and 12-dose pack sizes. Each dose lasts for one month.
7-10 business days
Get started by selecting a query from below or type your own query.
Jackie Zimmerman
Jackie Zimmerman
Carolynne Casale
Mary Leffner Powell
Carl