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Heartgard Plus Chewables for Medium Dogs 26-50lbs (Green)


Select Pet's Size

  • Upto 25lbs
  • Upto 25lbs (Nuheart)
  • 26 to 50lbs
  • 26 to 50lbs (Nuheart)
  • 51 to 100lbs
  • 51 to 100lbs (Nuheart)

Select Pack

  • 6 Doses
  • 12 Doses
Heartgard Plus Chewables for Medium Dogs 26-50lbs (Green) 6 Doses

Delivery Frequency

Uses: Treats roundworms, hookworms and prevents heartworms disease in dogs.

Doses: 1 Chew = 1 Month

  • Description
  • Key Benefits
  • Directions
  • Safety
  • More Info
  • FAQ

Heartgard Plus Chew for Medium Dogs, 26-50lbs (Green Box)

Treat medium-sized dogs with a weight of 26-50lbs.

HEARTGARD Plus green contains two active ingredients, Ivermectin and Pyrantel, that work together to prevent heartworm disease. It also controls hookworms and roundworms.

Heartgard Plus for medium dogs

How does Heartgard Plus Chews for Medium Dogs work?

Heartgard Plus Chewable includes Ivermectin, a broad-spectrum antiparasitic compound used to prevent heartworms in dogs by eliminating heartworm larvae that have infected them in the previous 30 days. Heartgard Plus prevents the disease by destroying larvae and preventing them from growing into juvenile and adult heartworms. Pyrantel Pamoate, an anthelmintics, is also present, which is used to prevent roundworms and hookworms. The monthly application of Heartgard Plus may assist to minimize the burden of roundworm eggs and hookworm larvae in the environment, lowering the risk of reinfection.

Heartgard Plus must be administered monthly, preferably on the same date each month. If given seasonally, the first dose must be given within 30 days of the dog's first exposure to mosquitoes. The last dose must be given within 30 days after the dog's last exposure to mosquitoes.


Administered orally at monthly intervals (recommended minimum dose level of 68 mcg of Ivermectin & 57 mg of Pyrantel of body weight).

Please consult a veterinarian before starting any treatment and ensure your dog is tested for heartworm disease.

Key Benefits

Heartgard Benefits:

  • Broad-spectrum antiparasitic treatment.
  • Delicious real-beef flavored monthly chew.
  • Protects dogs from heartworm disease.
  • Treats and controls hookworms and roundworms.
  • Easy to administer, readily accepted by dogs.
  • Safe for dogs and puppies 6 weeks of age or older.

Nuheart Benefits:

  • Highly effective for the prevention of heartworm disease.
  • Affordable and effective generic version of Heartgard.
  • The active ingredient is exactly the same as in Heartgard.
  • Each tablet contains exactly the same amount of ingredient.
  • Comes in a relatively small size that ensures easier dosing and less rejection.
  • Easy to administer meet flavor-based tablet for dogs.
  • For fussy eaters, it can be easily dissolved in a small amount of water or mixed with pet’s food.
  • Safe for dogs and puppies from 6 weeks of age.

Heartgard Chews Dosage for Dogs:

  • Get your pet tested for existing heartworm infection before you start the Heartgard Plus/Nuheart prevention program
  • If the pet is not infected by heartworms then start administering Heartgard Plus/Nuheart on a monthly basis
  • Give the oral treatment in accordance with the weight of the pet
  • On missing a monthly dosage, contact your veterinarian immediately for advice
  • You can also break down the tablet into pieces for ease of swallowing
  • Remove the tablet from the pack only at the time of administration

Heartgard Plus Chewables and Nuheart Tablets are available in three different color-coded packs. Weigh your pet first and choose the relevant package. Check the dosage table for details.

Heartgard Plus Chews Dosage for Dogs/Puppies (6 weeks and older puppies):

Dog Weight (lbs) No. of Dosage Dosage strength (mg)
Up to 25 lbs Administer one chew 68 mcg Ivermectin & 57 mg Pyrantel
26 to 50 lbs Administer one chew 136 mcg Ivermectin & 114 mg Pyrantel
51 to 100 lbs Administer one chew 272 mcg Ivermectin & 227 mg Pyrantel

Heartgard Plus Tips

Nuheart Dosage for Dogs/Puppies (6 weeks and older puppies):

Dog Weight (lbs) Dog Size No. of Dosage
Up to 25 lbs Small Administer one tablet
26 to 50 lbs Medium Administer one tablet
51 to 100 lbs Large Administer one tablet

Nuheart Tips

Heartgard Plus & Nuheart Safety Measures:

  • All dogs should be tested for heartworm infection before starting a preventive program.
  • Do not skip the monthly dosage, as there are chances of pets catching heartworm infections.
  • Ensure your dog consumes the entire dose.
  • Consult a vet if the dosage is missed for a period of more than 2 months.
  • Store in a cool and dark place away from sunlight. 


Important Note:

  • Consult a vet if the dosage is missed for a period of more than 2 months.
  • Do not administer to pets sensitive to the ingredients. Collie breed is more sensitive to the effects of Ivermectin administered at elevated dose levels. It is recommended to use in collies when used as recommended by the label.
More Info

Heartgard Plus

Target species 6 weeks and older puppies and dogs
Breed Size Small, Medium, Large for Dogs
Mode of administration Oral
Effective For Internal Parasites(Heartworms,Intestinal worms)
Active Ingredient Ivermectin and Pyrantel
Brand Name Heartgard Plus for Dogs


Target species 6 weeks and older puppies and dogs
Breed Size Small, Medium, Large for Dogs
Mode of administration Oral
Effective For Internal Parasites(Heartworms)
Active Ingredient Ivermectin
Brand Name Nuheart -Generic Heartgard for Dogs

Is Heartgard Plus safe to use in any breed of dog?

When used as directed, Heartgard Plus is safe and effective in any breed of dog. However, certain breeds like Collie are sensitive to Ivermectin, so it is advised to consult a vet before treating them. Additionally, all dogs should be tested for heartworm infection before starting a preventive program.


Is Heartgard Plus safe for pregnant dogs?

Heartgard Plus is clinically proven to be safe to use for pregnant and breeding dogs when treated with the recommended dose level.


How does Heartgard Plus Work?

When an infected mosquito transmits heartworm larvae to your dog, Heartgard Plus kills the developing larvae before they get to the bloodstream. Heartgard Plus prevents the larvae from developing into adult heartworms.


Does Heartgard Plus Kill Whipworms?

No, Heartgard Plus does not kill whipworms whereas it eliminates roundworms and hookworms.


Does Heartgard Plus Kill Fleas And Ticks?

No, Heartgard Plus is specifically designed to prevent heartworm infection and protect dogs against the dangers of heartworm disease.


What Happens If I Miss Giving A Dose Of Heartgard Plus Chewables?

The best thing if you missed is to check with your vet. If it is just two/three days, you can dose your dog. However, if it is more than a week or 15 days, it is safe to get your dog to diagnose for heartworm infection.


Still Have Questions? – Please email us your queries at and we will be happy to help you.

Customer Review

Overall Rating


433 reviews

Sort By:

Michael White

Heartgard Plus

Great pricing>>>Highly Recommend!!!!!

May 15, 2024

Jean Turnbaugh

As advertized

I have been buy for over 10 years from here. never been disappointed. Highly recommend

May 11, 2024


Heartgard Plus

My dog loves it when he gets his monthly dose, and he takes it without hesitation

May 04, 2024

terressa matthews

Good Rx for heartworm prevention

Like Canada Express & products

May 02, 2024

Dennis Mitchell

Excellent product

We've been using Heartgard Plus for years and our dogs have tolerated it well and no heart worms. Highly recommend.

May 01, 2024

Have A Question?

question-arrow Are your prices for 1 month or 6 months

next-arrow Heartgard Plus comes in 6 and 12-dose pack sizes. Each dose lasts for one month.

Jan 08, 2024
question-arrow Is Heartgard Plus also a flea and tick prevention
question-arrow I have ordered heartgard for my dog from another supplier but its delivery is too late. what is your delivery time? and when is the expiration date of your current stock?

next-arrow 7-10 business days

Apr 27, 2022
question-arrow I have 3 dogs over 51 lbs. but 1 is a puppy. Is this safe to give to a puppy?

next-arrow Your pet should be 6 weeks of age or older.

Apr 07, 2022
question-arrow Does generic Nuheart have the same dosage of ivermectin as Heartgard? AND does Nuheart also have pyrantel same as Heartgard?

next-arrow Nuheart has Ivermectin and Heartgard Plus have Ivermectin and Pyrantel.

Mar 21, 2022
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